Great progress has made in Twoline hybrid rice breeding in China. Up to 2010, a total of 427 twoline hybrid combinations were registered in China. Among them, 62 were nationally registered and titled as “super rice” by the Ministry of Agriculture, China. From 1993 to 2009, there were 121 combinations with the planting area over 6 700 hm2, and the total planting area reached 20.974 million hm2. With the planting area of 825×105 hm2 in 2002, Liangyoupeijiu ranked first among all hybrid combinations in planting area. In the following 7 years, twoline hybrid combination ranked first for 6 years, and second for one year. In recent years, twoline hybrid rice has become an important type in rice production in China, accounting for about 20% of the total planting area of hybrid rice. The current situation of the development of twoline hybrid rice was introduced, the main problems were discussed and the suggestions were proposed.