Bacteria isolated from healthy rice plant, infected rice plant, rhizosphere soils, water in paddy field and sclerotia showed antagonism to Thanatephorus cucumeris (Rhizoctonia solani). Most of the isolates inhibited mycelial growth of pathogen in vitro test. Some of the isolates could suppress the disease and protect the rice from infection in the greenhouse. Some isolates (1 out of 49) could promote rice seedling growth. The relative lesion length of rice sheath blight was significantly correlated with disease incidence (r2=0.33) but not the inhibition zone (r2=0.03) nor detached leaf lesion length (r2=0.12). The seedling dry weight was also not significantly correlated with relative lesion length (r2=0) nor disease incidence (r2=0.01). The isolating and screening way for effective isolates was also supposed.